TFF1 anticorps

N° du produit ABIN4901698

Cet anticorps Souris Monoclonal détecte spécifiquement TFF1 dans WB et ELISA. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour TFF1 anticorps (ABIN4901698)

Antigène: TFF1 (Trefoil Factor 1 (TFF1))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TFF1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-TFF1 anticorps

Fonction: HP-1α is a protein encoded by the CBX5 gene which is approximately 22,2 kDa. HP-1α is localised to the nucleus. It is involved in chromatin regulation and acetylation, E2F mediated regulation of DNA replication and aurora B signalling. It is a highly conserved non-histone protein that falls under the heterochromatin protein family. It has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain which is responsible for the homodimerization and interaction with a number of chromatin-associated non-histone proteins. It is also involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. HP-1α is expressed in the liver, nervous system, kidney, eye and intestine. Mutations in the CBX5 gene may result in Reynolds syndrome. STJ98895 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This primary antibody detects endogenous HP-1α protein.

Specificité: The antibody detects endogenous HP-1α protein.

Attributs du produit: Mouse Monoclonal to HP-1α.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Recombinant peptide derived from HP-1alpha.

Information d'application

Indications d'application: WB 1:500-2000
ELISA 1:10000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: -20 °C

Stockage commentaire: Store at -20°C, and avoid repeat freeze-thaw cycles.

Détails sur TFF1

Antigène: TFF1 (Trefoil Factor 1 (TFF1))

Autre désignation: HP-1alpha

Poids moléculaire: 22kDa

ID gène: 23468

UniProt: P45973

Pathways: EGFR Signaling Pathway